Listen to the “Meet the Mesothelioma Experts” Session with Dr. Joanna C. Horobin

COMMAND trialThe most recent installment of the Meso Foundation’s “Meet the Mesothelioma Experts” series is now available for listening on our website. The session was held on April 8 with Dr. Joanna C. Horobin, the Chief Medical Officer at Verastem, Inc. Dr. Horobin discussed the company’s latest investigational agent, defactinib, which is being developed for use in patients with pleural mesothelioma.

During the call, Dr. Horobin was interviewed by Mary Hesdorffer, the Meso Foundation’s executive director and experienced nurse practitioner. The session focused on learning more about investigational agent defactinib, which is used to delay the time to progression after having a response or stabilization with first-line therapy.

Dr. Joanna C. Horobin, M.B., Ch.B, has been the Chief Medical Officer at Verastem, Inc. since October 2012.

You can listen to the session with Dr. Horobin, as well as past “Meet the Mesothelioma Experts” session here.

Hypnosis Therapy may Decrease Fatigue in Mesothelioma Patients

RelaxationIt was recently reported that a clinical trial that randomized patients to receive hypnosis and cognitive therapy had a statistically significant reduction in their fatigue levels as compared to 79 percent of patients who did not have this intervention. The sudy was led by Guy Montgomery, PhD, Director of the Integrative Behavioral Medicine Program at Mount Sinai Hospital in New York.

Two hundred breast cancer patients who were undergoing radiation therapy were eligible to participate in this study. It was unusual to find that six months after the completion of radiation therapy, the intervention group reported less fatigue than 95% of the control group (patients who did not receive hypnosis and cognitive therapy). Mesothelioma patients often receive radiation therapy following the completion of an extrapleural pneumonectomy (EPP) or a Pleurectomy Decortication (PD). Though there are no studies currently underway in mesothelioma, it seems reasonable that patients who will be undergoing surgery plus radiation should be put in touch with integrative medicine to ascertain what services might be available to them.

A few years back, we invited a hypnotherapist to conduct a workshop at the Meso Foundation’s Symposium to aid the community in banishing negative thoughts usually implanted during the initial diagnosis when they were informed of the disease and prematurely provided with a prognosis from a doctor unfamiliar with mesothelioma. A positive outlook certainly does not cure the disease, but patients who are positive tend to eat better, engage with others, and less often fall victim to depression, which could impact their ability to function.

The study, recently published in the Journal of Clinical Oncology (2014; doi:10.1200/JCO.2013.49.3437

New Discovery: Asbestos Used in Byzantine Art

Asbestos fiberWhen we think of asbestos today, we often think of shipyards, construction sites, the automotive industry, and many other places the material was used merely decades ago. However, asbestos has a much longer history. Recent findings reported by LiveScience are now linking asbestos use to Byzantine artwork.

A new discovery from UCLA researchers reveals that Byzantine monks used asbestos in the 12th century as a coating for plaster beneath wall paintings. They found chrysotile, also known as white asbestos, in Cyprus at Enkleistra of St. Neophytos, a Byzantine monastery. By using the white asbestos in the plaster coating, the artist achieved a desirable, smooth surface for painting on the wall.

Researchers were not looking for asbestos, but made this discovery while studying the painting. They now plan to conduct further research into other artwork at the monastery and revisit other sites in Cyprus to see if the asbestos use was consistent. They hope to understand why the asbestos was used in this fashion during the time period.

Asbestos use is actually quite ancient and can be dated back 4,500 years to a time when it was mixed with clay to reinforce pottery. It has also been found in textiles dated 2,000 years ago that were used to make fireproof napkins. Asbestos made a comeback as a popular material in late 19th century industrial products, and it was used in construction for decades.

Due to the historical use of asbestos and its natural occurrence in soil, a countless number of people have been exposed to these fibers. Asbestos is a known carcinogenic material, and exposure is linked to the development of diseases, including mesothelioma, one of the most aggressive and deadly cancers. The latency period between asbestos exposure and development of mesothelioma ranges between 20-50 years, meaning that patients today were exposed decades ago, and patients of tomorrow have likely already been exposed.

Approximately 3,500 Americans are diagnosed with mesothelioma every year, and there is currently no cure. The Meso Foundation is the only non-government funder of peer-reviewed scientific research focused on prevention, early detection, development of effective treatments, and, ultimately, a cure for mesothelioma. You can learn more about this cancer and the asbestos-mesothelioma link at curemeso.org.

Stay Tuned this Fall for Two Regional Conferences on Mesothelioma

Mesothelioma regional conferences coming fall 2014.Following the successful conclusion of its annual Symposium, the Mesothelioma Applied Research Foundation (Meso Foundation) announced that later this year it will be the host of two regional conferences in Philadelphia and Chicago, for mesothelioma patients, their families, and others interested in learning about the most up-to-date information on mesothelioma treatment. In a cancer like mesothelioma, for which patients generally must travel far and often just to consult with experts, the ability to meet mesothelioma specialists, listen to their talks, and engage with them one-on-one, without leaving the conference venue, is unique , but also of utmost importance.

“Informed and knowledgeable patients generally can make better decisions regarding their treatment and care than those unaware of all options, side-effects, and other considerations,” said Mary Hesdorffer, experienced nurse practitioner and executive director of the Meso Foundation.

The three conferences, organized in conjunction with the University of Pennsylvania, University of Chicago, and the University of California San Francisco, are meant to provide patients across the country with similar, albeit condensed, benefits of the organization’s annual Symposium (expert presentations, support sessions, socialization with peers and experts), but with less travel and with only a one-day commitment.

The conferences will be scheduled as follows and more information will be made available a thttp://www.curemeso.org. The Foundation encourages everyone interested to sign up for its e-newsletter, through which it will make detailed conference information, including dates, available in the next few months.

September – at the University of Pennsylvania (Philadelphia)
October – at the University of Chicago (Chicago)
November – at the University of California San Francisco (San Francisco)

Thank You from Mary Hesdorffer

Mary Hesdorfferby Mary Hesdorffer, NP, Executive Director of the Meso Foundation

It feels like a time warp as we move from project to project, one day blending into the next. We are deeply immersed in planning three regional conferences before this year ends, and projecting what is in store for us in 2015.

I would like to take this opportunity to personally thank all of those who participated in our 2014 Symposium, which took place in early March. It is so important that we gather together to address the individual and global needs of the mesothelioma community. Weren’t our doctors amazing? I was so grateful that they came out in large numbers to support us and to impart valuable knowledge and support to those in need.

I would also like to thank the individual members of the staff who made the conference appear so effortless.

Erin Maas was responsible for the site location and all of the logistics that go along with running a conference. Thank you, Erin, for a job well done.

Maja Belamaric and Beth Posocco were in charge of communications and marketing the conference, work that is not always visible to the public. The live stream attracted nearly 600 viewers thanks to their tireless efforts to ensure that it was properly managed and advertised.

Erica Ruble was the unofficial hostess of the event making sure that everyone was welcomed and warmly introduced to others. Her fundraising knowledge and encouragement to others has helped us to grow exponentially.

Dana Purcell was responsible for planning many of the supportive care and fundraising sessions. I think we can all testify to a job well done and we look forward to her continued work on community events and individual fundraisers over the upcoming year.

Last but not least is our government affairs director, Jessica Barker. Jessica is well-known on the hill championing our causes and making valuable connections with politicians and government entities to provide our community with a strong voice in Washington. You will see Jessica making her rounds to many political events and she is a sage advisor to both Melinda and me. If you are planning to attend the ADAO conference taking place in Washington, DC in April, please introduce yourself to Jessica as she will be representing the Foundation at this asbestos-focused event. Unfortunately, I will be unable to attend, but I wish Linda Reinstein a successful conference.

Finally, our CEO Melinda is really owed a debt of gratitude for managing the business side of the Foundation and ensuring our financial health so we can remain strong in achieving the goals of our mission. It is a pleasure to work closely with Melinda as she brings her impressive non-profit background into the discussion and helps me to advance the scientific agenda of the Foundation, proving continuously that two heads are better than one!

Keep in close touch with me and let me know your thoughts on how we are doing. Also, we will soon be announcing the date and time for another telephonic town-hall meeting to discuss the future and current state of the Foundation.